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New gout drug shows promise in lowering uric acid levels

NCT ID NCT03934099

Disease control Sponsor: LG Chem Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tested a new medicine called LC350189 in 156 adults with gout and high uric acid. The goal was to see if different doses could safely lower uric acid below target levels over 12 weeks. Participants took the drug or a placebo, and researchers measured uric acid in the blood at several time points.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Phase 2

Tests whether the treatment actually works, and watches for side effects, in a larger group.

Participants

156 people

The number who actually took part.

Started

Dec 2019

Finished

May 2021

Lead sponsor

A company

The lead sponsor is a pharmaceutical, biotech, or medical-device company.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 to 75 years

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: 1. Subjects or the subject's legally acceptable representatives who sign a written informed consent form prior to the initiation of any study procedures. 2. Subjects with hyperuricemia and a history or presence of gout per American College of Rheumatology (ACR) criteria. Exclusion Criteria: 1. Subjects with secondary hyperuricemia (e.g., due to myeloproliferative disorder, or organ transplant). 2. Subjects experiencing an active acute gout attack within 3 weeks prior to screening (Visit 1).

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Conditions

The condition(s) this trial relates to.

gout Hyperuricemia

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Gout Hyperuricemia

Contacts and locations

Locations

  • Advanced Clinical Research

    West Jordan, Utah, 84088, United States

  • Altoona Center For Clinical Research

    Duncansville, Pennsylvania, 16635, United States

  • Avant Research Associates

    Austin, Texas, 78704, United States

  • Avita Clinical Trials

    Tampa, Florida, 33613, United States

  • Clinical Research Trials of Florida, Inc

    Tampa, Florida, 33607, United States

  • Discovery MM Services Incorporated

    Houston, Texas, 77450, United States

  • Dominion Medical Associates

    Richmond, Virginia, 23219, United States

  • Health Awareness Inc

    Jupiter, Florida, 33458, United States

  • IACT Health

    Columbus, Georgia, 31904, United States

  • Meridien Research

    Maitland, Florida, 32751, United States

  • Meridien Research

    St. Petersburg, Florida, 33709, United States

  • Miami Dade Medical Research Institute

    Miami, Florida, 33176, United States

  • Olive Branch Family Medical Cente

    Olive Branch, Mississippi, 38654, United States

  • OnSite Clinical Solutions

    Charlotte, North Carolina, 28226, United States

  • OnSite Clinical Solutions

    Charlotte, North Carolina, 28277, United States

  • Paramount Medical Research and Consulting

    Middleburg Heights, Ohio, 44130, United States

  • Preferred Research Partner

    Little Rock, Arkansas, 72211, United States

  • Quality Clinical Research

    Omaha, Nebraska, 68114, United States

  • Synexus Clinical Research

    Birmingham, Alabama, 35211, United States

  • Synexus Clinical Research

    Chandler, Arizona, 85224, United States

  • Synexus Clinical Research

    Mesa, Arizona, 85206, United States

  • Synexus Clinical Research

    Tucson, Arizona, 85712, United States

  • Synexus Clinical Research

    Chicago, Illinois, 60602, United States

  • Synexus Clinical Research

    Richfield, Minnesota, 55423, United States

  • Synexus Clinical Research

    St Louis, Missouri, 63141, United States

  • Synexus Clinical Research

    Omaha, Nebraska, 68144, United States

  • Synexus Clinical Research

    Henderson, Nevada, 89052, United States

  • Synexus Clinical Research

    Akron, Ohio, 44311, United States

  • Synexus Clinical Research

    Cincinnati, Ohio, 45236, United States

  • Synexus Clinical Research

    Columbus, Ohio, 43212, United States

  • Synexus Clinical Research

    Anderson, South Carolina, 29621, United States

  • Synexus Clinical Research

    Dallas, Texas, 75234, United States

  • Synexus Clinical Research

    San Antonio, Texas, 78229, United States

  • Synexus Clinical Research

    Salt Lake City, Utah, 84123, United States

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