Can GM-CSF turn the tide for children with sepsis?

NCT ID NCT05266001

Completed Disease control Sponsor: Nationwide Children's Hospital Source: ClinicalTrials.gov ↗

First seen Apr 15, 2026 · Last updated May 21, 2026 · Updated 3 times

Summary

This study tested whether the drug GM-CSF could help children with sepsis who have a weakened immune system. 141 children with multiple organ failure were given either GM-CSF or a placebo. The goal was to see if the drug could improve organ function and quality of life over 28 days and 3 months.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

Get updates

Get notified about this study

Sign up to get updates when this study changes or when new studies for PEDIATRIC SEPSIS-INDUCED MULTIPLE ORGAN DYSFUNCTION SYNDROME are added.

Vår säkerhetsrekommendation!

Genom att skicka in godkänner du våra Användarvillkor

Contacts and locations

Show contact details

Locations

Arkansas Children's Hospital

Little Rock, Arkansas, 72202, United States
Benioff Children's Hospital - Mission Bay

San Francisco, California, 94143, United States
Benioff Children's Hospital - Oakland

Oakland, California, 64609, United States
CS Mott Children's Hospital

Ann Arbor, Michigan, 48109, United States
Children's Hospital Colorado

Aurora, Colorado, 80045, United States
Children's Hospital of Los Angeles

Los Angeles, California, 90027, United States
Children's Hospital of Michigan

Detroit, Michigan, 48202, United States
Children's Hospital of Minnesota

Minneapolis, Minnesota, 55404, United States
Children's Hospital of Orange County

Orange, California, 92868, United States
Children's Hospital of Philadelphia

Philadelphia, Pennsylvania, 19104, United States
Children's Hospital of Pittsburgh

Pittsburgh, Pennsylvania, 15260, United States
Children's Hospital of San Antonio

San Antonio, Texas, 78207, United States
Children's National Medical Center

Washington D.C., District of Columbia, 20010, United States
Duke University

Durham, North Carolina, 27705, United States
Medical College of Wisconsin

Milwaukee, Wisconsin, 53233, United States
Medical University of South Carolina

Charleston, South Carolina, 29425, United States
Mercy Children's Hospital

Kansas City, Missouri, 64108, United States
Nationwide Children's Hospital

Columbus, Ohio, 43205, United States
Pennsylvania State University

Hershey, Pennsylvania, 17033, United States
Primary Children's Hospital

Salt Lake City, Utah, 84158, United States
Rainbow Babies and Children's Hospital

Cleveland, Ohio, 44106, United States
Texas Children's Hospital

Houston, Texas, 77030, United States
University of California - Davis

Sacramento, California, 95618, United States
University of Minnesota

Minneapolis, Minnesota, 55455, United States
Virginia Commonwealth University

Richmond, Virginia, 23298, United States

Conditions

Explore the condition pages connected to this study.

PEDIATRIC SEPSIS-INDUCED MULTIPLE ORGAN DYSFUNCTION SYNDROME