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Blood sugar rollercoaster linked to stroke death risk

NCT ID NCT04001049

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This completed study looked at 192 adults with acute ischemic stroke to see if large swings in blood sugar (glycemic variability) are linked to worse outcomes, including death and disability. Participants wore a continuous glucose monitor for 96 hours. The goal was to understand whether unstable blood sugar predicts poorer recovery, which could guide future treatment strategies.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

What this could lead to
If successful, this could help doctors understand which stroke patients need tighter blood sugar control to improve survival and recovery.
What could go wrong
This is an observational study, not a treatment trial. It cannot prove that controlling blood sugar directly improves outcomes, only that a link may exist.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Participants

192 people

The number who actually took part.

Started

Jun 2020

Finished

Dec 2022

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Who is studied

Patients \> 18 years old presenting with acute ischemic stroke of less than 24 hours of evolution

Ages

18 years and older

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * \> 18 years old * Inclusion less than 24 hours from ischemic stroke * Functional independence prior to stroke * Signed informed consent Exclusion Criteria: * Transient cerebral ischemia * Prevision of need to perform a magnetic resonance within the first 96 hours from inclusion * Concomitant severe or deadly disease that may interfere with study follow-up during 3 months from stroke * Current drug or alcohol abuse that may interfere with study follow-up * Participation in a clinical trial

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Hospital Universitario La Paz

    Madrid, 28046, Spain

More trials for these conditions

Other studies related to the condition(s) this trial covers.