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Gut hormone GLP-1 may influence bone strength, new study finds

NCT ID NCT06722560

Knowledge-focused Sponsor: Odense University Hospital Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study looked at how a natural gut hormone called GLP-1 affects bone health in 12 healthy volunteers. Participants received either GLP-1 or a saltwater solution for three days using a small pump. Researchers measured changes in bone formation and breakdown markers to understand how GLP-1 might help regulate bone turnover.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

12 people

The number who actually took part.

Started

Jan 2025

Finished

Oct 2025

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 to 40 years

Sex

Anyone

Healthy volunteers

Accepted

You do not need to have the condition being studied to take part.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Healthy Exclusion Criteria: * Diabetes mellitus including prediabetes (Hb1Ac \>42 mmol/mol at baseline) * BMI \> 28 kg/m2 * Conditions and pharmaceutical treatments that influence bone metabolism (e.g., bone fractures \< 6 months, uncontrolled thyrotoxicosis, and severe renal impairment). * Pregnancy * Inability to complete all investigations or to provide informed consent

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As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Healthy volunteer To investigate the physiological effect of GLP-1 on the skeleton

Contacts and locations

Locations

  • Department of Endocrinology, University Hospital of Odense

    Odense, 5000, Denmark

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