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New combo therapy targets high-risk lymphoma patients

NCT ID NCT04980222

First seen Nov 18, 2025 · Last updated Apr 29, 2026 · Updated 23 times

Summary

This study tests a new drug, glofitamab, added to standard chemotherapy (R-CHOP) for people with a fast-growing type of lymphoma that has a high risk of coming back. The goal is to see if the combination is safe and works better at controlling the cancer. About 46 adults with untreated diffuse large B-cell lymphoma will take part.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • Aarhus Universitetshospital Skejby

    Aarhus N, 8200, Denmark

  • Baylor University Medical Center

    Dallas, Texas, 75204, United States

  • Centre Henri Becquerel

    Rouen, 76038, France

  • City of Hope Comprehensive Cancer Center

    Duarte, California, 91010, United States

  • Hopital Henri Mondor

    Créteil, 94010, France

  • Hospital Clinic i Provincial de Barcelona

    Barcelona, 08036, Spain

  • Hospital Clinico Universitario de Salamanca

    Salamanca, 37007, Spain

  • Hospital General Universitario Gregorio Marañon

    Madrid, 28007, Spain

  • Hospital Univ. 12 de Octubre; Servicio de Hematologia

    Madrid, 28041, Spain

  • Memorial Sloan Kettering Bergen

    Montvale, New Jersey, 07645, United States

  • Memorial Sloan Kettering Cancer Center

    New York, New York, 10065, United States

  • Memorial Sloan Kettering Cancer Center at Westchester

    Harrison, New York, 10604, United States

  • Stanford Cancer Center

    Stanford, California, 94305-5820, United States

  • Universitair Medisch Centrum Groningen

    Groningen, 9713 GZ, Netherlands

  • University of Iowa

    Iowa City, Iowa, 52242, United States

  • Uniwersytecki Szpital Kliniczny; Klinika Hematologii, Nowotworów Krwi i Transplantacji Szpiku

    Wroclaw, 50-367, Poland

  • Uniwersyteckie Centrum Kliniczne, Klinika Hematologii i Transplantologii

    Gdansk, 80-211, Poland

  • Washington University; Wash Uni. Sch. Of Med

    St Louis, Missouri, 63110, United States

Conditions

Explore the condition pages connected to this study.