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Worldwide kidney study tracks 6,000 patients to unlock disease secrets

NCT ID NCT04389827

Knowledge-focused Sponsor: The George Institute Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study followed nearly 6,000 people with kidney disease from around the world. Researchers collected routine test results like kidney function and protein in urine to better understand how the disease progresses. The goal was to gather information, not to test a new treatment.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Participants

5,999 people

The number who actually took part.

Started

May 2020

Finished

Oct 2025

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Who is studied

Participants will be recruited from units that provide a comprehensive nephrology service

Ages

2 to 80 years

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: 1. Documented diagnosis of primary kidney disease 2. Regular visits (6-12 monthly) with a physician at a participating site that includes the monitoring of protein in urine and kidney function 3. eGFR \> 25 ml/min/1.73m2 4. ≥ 2 to ≥ 80 years of age 5. One of the following laboratory urine parameters within 12 months of screening meeting the values of: * Urine Albumin-to-Creatinine Ratio (UACR) \> 200 mg/g OR * Protein-to-Creatinine Ratio (PCR) \> 300 mg/g OR * Albumin Excretion Rate (AER) \> 200 mg/day OR * 24 hour Albumin Excretion \> 200 mg/day OR * 24 hour Urine Protein Excretion \> 300 mg/day 6. Willing and able to sign informed consent 7. Willing to be approached about participation in interventional research studies Exclusion Criteria: 1. Life-expectancy of less than 6 months 2. Currently receiving renal replacement therapy or planned to start in the next 6 months 3. Planned transplant in the next 6 months 4. Currently participating in a clinical trial involving investigational medicinal product (exception is participation in studies implemented through the GKPTN)

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Conditions

The condition(s) this trial relates to.

chronic renal failure syndrome diabetic kidney disease focal segmental glomerulosclerosis glomerulonephritis hypertensive nephropathy IgA glomerulonephritis impaired renal function disease kidney disorder lipoid nephrosis membranous glomerulonephritis

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Kidney diseases

Contacts and locations

Locations

  • The George Institute

    Sydney, New South Wales, 2031, Australia

More trials for these conditions

Other studies related to the condition(s) this trial covers.