Scientists uncover how gut hormones work without a pancreas
NCT ID NCT06895408
First seen Jun 24, 2026 · Last updated Jun 24, 2026
Summary
This completed study looked at how two gut hormones, GIP and GLP-1, affect the body outside the pancreas. Researchers gave these hormones separately and together to 12 adults who had their pancreas removed. By measuring blood sugar, fat, and bone markers, they hope to understand why new combination drugs for diabetes and obesity work so well.
Disclaimer
Read more
Show less
This is a summary of
the original study
.
Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
Get updates
Get notified about this study
Sign up to get updates when this study changes or when new studies for PANCREATECTOMY; HYPERGLYCEMIA are added.
Genom att skicka in godkänner du våra Användarvillkor
Contacts and locations
Show contact details
Enter your email to view the contact information for this study.
Genom att skicka in godkänner du våra Användarvillkor
Locations
-
Center for Clinical Metabolic Research, Gentofte Hospital
Hellerup, 2900, Denmark
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
Glucose-dependent Insulinotropic Polypeptide (GIP) and Glucagon-Like Peptide 1 (GLP-1)
What this could lead to
If successful, this could clarify why combined GIP/GLP-1 drugs work better than GLP-1 alone, potentially leading to improved treatments for diabetes and obesity.
What could go wrong
This is a small, completed study with only 12 participants, all of whom had their pancreas removed. Results may not apply to the general population, and the study only measures short-term effects.
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.