Gum thickening breakthrough: your own blood may save your smile!
NCT ID NCT07521527
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study tests a new, gentle way to thicken thin gums using a substance made from your own blood (called i-PRF). Thin gums can lead to gum recession and other problems. The treatment involves a few injections over time, and researchers will measure gum thickness with ultrasound for 6 months. It aims to improve gum health and appearance without major surgery.
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Study facts
What this study's own registry entry says, in plain language.
- Phase
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Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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About 20 people
The number the study aims to enrol. It can still change while the study runs.
- Started
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Apr 2026
- Expected to finish
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Jan 2027
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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18 years and older
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Systemically healthy individuals aged ≥18 years * Non-smokers or light smokers (≤10 cigarettes per day) * Individuals with full-mouth plaque score (FMPS) \<15% and full-mouth bleeding score (FMBS) \<15% * Individuals with gingival thickness \<0.8 mm in the mandibular anterior teeth to be treated * Periodontally healthy individuals with probing depth (PD) ≤3 mm in the mandibular anterior teeth * Absence of structural defects, crowns, or large restorations in the mandibular anterior teeth * Absence of missing or supernumerary teeth in the mandibular anterior region * No history of blood-borne infectious diseases * No systemic diseases or medical conditions Exclusion Criteria: * Individuals under 18 years of age * Pregnancy or breastfeeding * Presence of periodontal pockets \>4 mm * Presence of structural defects, crowns, or large restorations in the teeth * Presence of systemic diseases or coagulation disorders * Use of anticoagulant medications * Ongoing orthodontic treatment with active tooth movement * Use or history of medications affecting periodontal tissues (e.g., immunosuppressive drugs, calcium channel blockers, anticonvulsants) * History of periodontal surgery in the area to be treated
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As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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Çanakkale Onsekiz Mart University
Çanakkale, Turkey (Türkiye)
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