Supplement study sees if testosterone gets a boost
NCT ID NCT06747624
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study tested whether a supplement called geranylgeraniol (GG) can raise testosterone levels in healthy men and women aged 40 to 65. Researchers measured total and free testosterone in 34 participants over 18 weeks using a crossover design. The goal was to see if GG improves hormone levels and self-reported health, but this is an early-stage investigation, not a treatment for any disease.
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Study facts
What this study's own registry entry says, in plain language.
- Phase
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Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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34 people
The number who actually took part.
- Started
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Jan 2025
- Finished
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Sep 2025
- Lead sponsor
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A company
The lead sponsor is a pharmaceutical, biotech, or medical-device company.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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40 to 65 years
- Sex
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Anyone
- Healthy volunteers
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Accepted
You do not need to have the condition being studied to take part.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: 1. Males and females between 40 to 65 years of age. 2. Individuals with no significant history of inflammatory bowel disease (i.e. ulcerative colitis, Crohn's, Celiac, etc.), ulcers, liver and/or kidney disease or other any acute or chronic dis-ease. 3. Ability to read and speak English 4. Subject's agreement to voluntarily participate in the study 5. Negative pregnancy test confirmed with serum HCG on initial baseline testing and baseline testing at the start of the crossover (at 10 weeks) Exclusion Criteria: 1. Males and females under 40 or over 65 years of age 2. Previous (in the past 60 days) or current hormone replacement therapy 3. Males and females with free testosterone levels over normal range 4. History of hysterectomy, oophorectomy, or orchiectomy 5. Current biotin supplementation \>3 mg per day one week prior to the start of the study 6. Current or history of smoking 7. CoQ10/Ubiquinol supplementation within the past 2 weeks 8. Current use of hormone boosting supplements (i.e. fenugreek, shilajit, tongkat ali, ashwagandha) within the past 4 weeks 9. Current or previous use of medication - NSAIDS, statins, blood thinners, H2 blockers and PPI or blood sugar-lowering agents. 10. Diabetes 11. Cancer 12. Hemophilia 13. Disorders of heart, kidney, lung or liver function 14. Infectious diseases 15. Alcohol or drug abuse (\>7 drinks per week for men and women) 16. Pregnancy, lactation, or individuals planning to become pregnant in the next 6 months 17. Failure to submit statement of consent 18. Participant in a clinical trial in the previous 30 days.
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As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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Designs for Health, Inc.
Palm Coast, Florida, 32164, United States
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