Genetic test could shorten hospital stays for fungal infection patients
NCT ID NCT03554239
First seen Jun 29, 2026 · Last updated Jun 30, 2026 · Updated 1 time
Summary
This study explores whether a genetic test (CYP2C19) can help doctors choose the right dose of the antifungal drug voriconazole more quickly. Patients starting voriconazole for an infection will give a blood sample for genotyping. The goal is to see if this personalized dosing reduces the number of days spent in the hospital compared to standard monitoring.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- genetic test (CYP2C19 genotyping)
- What this could lead to
- If successful, this approach could help doctors personalize antifungal dosing, potentially shortening hospital stays and reducing side effects.
- What could go wrong
- This is a small, early-stage study focused on feasibility. Genetic testing may not significantly change outcomes, and results may not apply to broader populations.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Phase
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Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Started
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Dec 2016
- Finished
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Dec 2017
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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Children (under 18), adults (18 to 64) and older adults (65 and over)
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Patient with Voriconazole treatment * Man or woman * With social security number Exclusion Criteria: * Patient or parent of patient who refuse to accept inform consent form * All patient under protection of adults
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
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