Teen suicide gene hunt: can DNA predict risk?
NCT ID NCT02001649
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study looked at whether certain genetic variations are more common in teenagers who have attempted suicide. Researchers analyzed DNA from 250 teens (half who attempted suicide, half who did not) to see if specific genes linked to brain function might increase risk. The goal is to better understand biological factors behind suicidal behavior, not to test a new treatment.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- What this could lead to
- If successful, this could help identify genetic risk factors for suicide attempts in adolescents, potentially guiding future prevention strategies.
- What could go wrong
- This is an observational genetic study, not a treatment trial. It cannot prove cause and effect, and results may not apply to all populations.
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Study facts
What this study's own registry entry says, in plain language.
- Phase
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Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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250 people
The number who actually took part.
- Start date
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Dec 2013
- Finished
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Jul 2016
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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13 to 17 years
- Sex
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Anyone
- Healthy volunteers
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Accepted
You do not need to have the condition being studied to take part.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: Case : * Age at admission between 13 and 17 years old * Hospitalized for attempted suicide * Absence of prominent mental retardation or organic brain damage * Fluent in French * Able to comprehend the study procedures and to undergo entry assessments safely * Provided written informed consent for study participation, and additional consent from the patient's parents or guardians * Northern and Western European ancestry (HapMap-CEU) * Medical insurance coverage Control : * Healthy adult volunteers * No present or past psychiatric illness * No personal history of suicidal behavior and without a family history of suicide * Provided written informed consent for study participation * Northern or Western European ancestry (HapMap-CEU) * Medical insurance coverage Exclusion Criteria: Case: * Inability to get an informed and valid consent * Home address outside the selected hospitals' geographic areas * Intellectual disability or organic brain damage * Origine ethnique non CEU * Absence of medical insurance coverage * Pregnant or lactating women * Without Northern or Western European ancestry (HapMap-CEU) Control : * Inability to get an informed and valid consent * Intellectual disability or organic brain damage * History of suicidal behavior * Psychiatric disorder, past or present * Family history of suicide * Borderline personality disorder * Absence of medical insurance coverage * Pregnant or lactating women * Without Northern or Western European ancestry (HapMap-CEU)
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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Chu Rouen
Rouen, Haute Normandie, 76000, France
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