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Scientists hunt for genetic clues to prevent Age-Related muscle decline

NCT ID NCT07658612

Knowledge-focused Sponsor: Chang Gung University of Science and Technology Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study investigates links between genetics, oral muscle function, and sarcopenia (age-related muscle loss) in adults aged 60 and older. Researchers will collect saliva samples and measure grip strength, walking speed, and chewing ability. The goal is to understand how specific genes may influence sarcopenia risk and to develop better screening tools.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

What this could lead to
If successful, this could point toward personalized prevention strategies for sarcopenia based on genetic types.
What could go wrong
This is an observational study, not a treatment trial. It may only show correlations, not causes, and results may not apply to all populations.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Participants

251 people

The number who actually took part.

Started

Nov 2025

Finished

Jun 2026

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Who is studied

The research locations are the multimedia classroom on the 5th floor of the Department of Health and Nutrition at Chang Gung University, as well as community care centers in various districts of Taoyuan City and New Taipei City.

Ages

60 years and older

Sex

Anyone

Healthy volunteers

Accepted

You do not need to have the condition being studied to take part.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Case group - Inclusion Criteria: * aged 60 years (inclusive) or older * general public or residing in an institution for 3 months (inclusive) or more * willing to participate in the experimental design and sign the consent form * able to eat independently by mouth * identified by researchers as possibly having sarcopenia Control group-Inclusion Criteria: * aged 60 years (inclusive) or older * general public or residing in an institution for 3 months (inclusive) or more ●willing to participate in the experimental design and sign the consent form * able to eat independently by mouth * identified by researchers as not possibly having sarcopenia Case group 、Control group- Exclusion Criteria: * having comorbidities, critical illnesses, undergoing major surgeries, cancer, renal failure, liver failure, kidney diseases, liver diseases, having malignant tumors in the past five years, inflammation symptoms (C-reactive protein \>10mg/dl) * severely malnourished individuals (GNRI \< 82) * long-term tube-fed individuals.

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Conditions

The condition(s) this trial relates to.

Sarcopenia

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Non-sarcopenic subjects Possible sarcopenia Sarcopenia (with low asm by bim)

Contacts and locations

Locations

  • Chang Gung University of Science and Technology

    Taoyuan, Taiwan

More trials for these conditions

Other studies related to the condition(s) this trial covers.