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Scientists hunt for genes behind hearing loss and dizziness

NCT ID NCT00023049

Knowledge-focused Sponsor: National Institute on Deafness and Other Communication Disorders (NIDCD) Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 25, 2026 · Last updated Sep 17, 2026 · Updated 7 times

Summary

This study aims to find the genetic causes of hereditary hearing loss and balance disorders. Researchers will study families with these conditions, collecting medical history, blood or cheek swabs, hearing and balance tests, and sometimes scans. The goal is to identify genes and mutations that lead to these disorders, which could improve diagnosis and understanding.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

What this could lead to
If successful, this research could help identify genes behind hearing and balance disorders, leading to better genetic tests and future treatments.
What could go wrong
This is an observational study, not a treatment trial. It may not directly benefit participants, and finding specific genes can be complex and time-consuming.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Participants

335 people

The number who actually took part.

Started

Dec 2002

Lead sponsor

A government research agency

The lead sponsor is the US National Institutes of Health.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Who is studied

We will be studying up to 750 people with hearing losses or balance problems that are thought to be hereditary and, if possible, their family members, either with or without hearing or balance problems to participate in our study. A total of up to 400 affected and unaffected individuals, including family members and control subjects will be enrolled from the Nigerian population.

Ages

Up to 99 years

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

* INCLUSION CRITERIA: Persons with known SNHL and/or peripheral vestibular dysfunctions caused by genetic etiology Family members of persons with known SNHL and/or peripheral vestibular dysfunction caused by genetic etiology Adults must be able to provide informed consent Minors must have a parent or guardian able to provide informed consent Subjects must be 0-99 years of age For Nigeria subjects with non-syndromic hearing loss, their hearing loss must be early-onset, before 10 years of age, to be eligible. EXCLUSION CRITERIA: Persons with SNHL and/or peripheral vestibular dysfunction caused by a nongenetic etiology such as trauma, infection, metabolic or immunologic disorders, or exposure to ototoxic agents such as noise or aminoglycoside antibiotics will not be included in this protocol.

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Conditions

The condition(s) this trial relates to.

Deafness hearing disorder hearing loss disorder Hearing Loss, Sensorineural sensorineural hearing loss disorder vestibular disorder X-linked mixed hearing loss with perilymphatic gusher

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Hearing disorder Sensorineural hearing loss Vestibular disease

Contacts and locations

Locations

  • Institute of Child Health, College of Medicine, University of Ibadan

    Ibadan, Nigeria

  • National Institutes of Health Clinical Center

    Bethesda, Maryland, 20892, United States

More trials for these conditions

Other studies related to the condition(s) this trial covers.