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One-Time gene shot could free hemophilia patients from frequent infusions

NCT ID NCT07548411

First seen Apr 25, 2026 · Last updated May 22, 2026 · Updated 4 times

Summary

This study tests a one-time gene therapy called GS1191-0445 in 7 Chinese men with severe hemophilia A. The treatment uses a harmless virus to deliver a working gene to the liver, so the body can produce its own clotting factor VIII. The goal is to see if it is safe and reduces the need for regular factor infusions.

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Contacts and locations

Locations

  • Institute of Hematology & Blood Diseases Hospital Chinese Academy of Medical Sciences & Peking Union Medical College

    Tianjin, Tianjin Municipality, 300020, China

  • Union Hospital, Tongji Medical College, Huazhong University of Science and Technology

    Wuhan, Hubei, 430022, China

Conditions

Explore the condition pages connected to this study.