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Gene therapy targets deadly heart damage in rare neurological disease

NCT ID NCT05445323

Summary

This early-stage trial is testing whether a single dose of LX2006 gene therapy can safely treat heart muscle damage in people with Friedreich's ataxia. The therapy delivers a healthy gene directly to heart cells to improve their function. Eight participants with confirmed Friedreich's ataxia and heart involvement will be followed for five years to check safety and whether heart function improves.

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Contacts and locations

Locations

  • Ataxia Center and HD Center of Excellence, University of California

    Los Angeles, California, 90095, United States

  • Mayo Clinic

    Rochester, Minnesota, 55905, United States

  • University of South Florida

    Tampa, Florida, 33612, United States

Conditions

Explore the condition pages connected to this study.