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Scientists compare nose and lung cells to unlock allergy secrets

NCT ID NCT01923519

Knowledge-focused Sponsor: Centre Hospitalier Universitaire de Nice Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study looked at gene activity in cells from the nose and lungs of 44 healthy and allergic adults. The goal was to understand how allergies change these cells and why the nose and lungs react differently. Researchers hope this knowledge will lead to better treatments for allergic airway diseases.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

What this could lead to
If successful, this research could help explain how allergies affect the airways and point toward new targets for treatment.
What could go wrong
This is a small, completed observational study that does not test any treatment. Its findings may not lead directly to new therapies.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

44 people

The number who actually took part.

Started

Nov 2013

Finished

May 2017

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 to 30 years

Sex

Anyone

Healthy volunteers

Accepted

You do not need to have the condition being studied to take part.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * age ≥ 18 years and \<30 years * isolated allergic rhinitis according to clinical criteria ARIA * absence of asthma whose diagnosis is made based on clinical criteria or mild to moderate persistent asthma controlled with a diagnosis is made based on clinical criteria Exclusion Criteria: * recent rhino-bronchial infection (\<6 weeks) * asthma exacerbation in the previous 6 weeks * Chronic disease may in the opinion of the investigators interfere with the results of the study or expose them to additional risk. * Treatment with nasal corticosteroids, inhaled or systemic in the past 6 weeks * Current smoking no history of smoking or not smoking for at least 12 months and weaned smoking history \<5 pack-years) * Special Needs

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Conditions

The condition(s) this trial relates to.

allergic disease allergic rhinitis asthma

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Allergy

Contacts and locations

Locations

  • Hôpital Pasteur

    Nice, 06003, France

More trials for these conditions

Other studies related to the condition(s) this trial covers.