Ultrasound reveals hidden stomach risks in semaglutide users

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion criteria for the semaglutide cohort are: * Adults (\>=18 years old) * Semaglutide therapy for any indication (type 2 diabetes or weight loss) * Semaglutide therapy at any dose * Semaglutide therapy with any route of administration * Semaglutide therapy administered daily or weekly * Semaglutide therapy at any time since initiation * Elective surgery of any kind for which general anaesthesia was planned preoperatively * Adherence to current ASA recommendation regarding GLP-1-RA; i.e. holding semaglutide for 1 week if administered weekly or for 1 day if administered daily. * Adherence to current ESAIC fasting guidelines; i.e. \>2 hours for liquids and \>6 hours for solid foods. Inclusion criteria for the control cohort are: * Adults (\>=18 years old) * Elective surgery of any kind for which general anaesthesia was planned preoperatively * Adherence to current ESAIC fasting guidelines; i.e. \>2 hours for liquids and \>6 hours for solid foods Exclusion criteria for the semaglutide cohort are: * Semaglutide not held in accordance with current ASA recommendation, i.e. held either longer or shorter than recommended. * No adherence to current ESAIC fasting guideline * Presence of a contra-indication to gastric ultrasound; i.e. previous gastric surgery (e.g. partial gastrectomy, gastric bypass) or hiatal hernias. * Presence of comorbidities associated with delayed gastric emptying: scleroderma, systemic lupus erythematosus, hypothyroidism, Parkinson disease, cerebral palsy, and multiple sclerosis. * Inability to assume the right lateral decubitus position * Initial anaesthetic plan did not involve general anaesthesia, e.g. neuraxial or locoregional cases Exclusion criteria for the control cohort are: * Semaglutide or other GLP-1-RA therapy * No adherence to current ESAIC fasting guideline * Presence of a contra-indication to gastric ultrasound; i.e. previous gastric surgery (e.g. partial gastrectomy, gastric bypass) or hiatal hernias * Presence of comorbidities associated with delayed gastric emptying: scleroderma, systemic lupus erythematosus, hypothyroidism, Parkinson disease, cerebral palsy, and multiple sclerosis * Inability to assume the right lateral decubitus position * Initial anaesthetic plan does not involve general anaesthesia, e.g. locoregional cases