Stomach speed may hold clues to obesity and diabetes risk
NCT ID NCT07188571
First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This completed observational study looked at how quickly food leaves the stomach (gastric emptying) in 163 people with simple obesity. Researchers used a special scan to measure stomach emptying time and checked how it relates to blood sugar and fat levels. The goal is to better understand the link between stomach function and metabolic problems like type 2 diabetes. No treatment was given; the study only analyzed existing medical data.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- What this could lead to
- If successful, this study could help doctors better understand how stomach emptying affects metabolism in obesity, potentially improving risk assessment and weight-loss strategies.
- What could go wrong
- This is an observational study, not a treatment trial. It only looks at existing data and does not test any new drug or intervention, so it cannot directly lead to a cure or therapy.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Participants
-
163 people
The number who actually took part.
- Started
-
Jul 2025
- Finished
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Aug 2025
- Lead sponsor
-
Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
Who is studied
Participants included in the study were diagnosed with obesity, aged 18-65 years, without severe wasting diseases, who had not received medication affecting gastric motility, and who had no contraindications for gastric emptying scintigraphy or blood sampling.
- Ages
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18 to 65 years
- Sex
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Anyone
- Healthy volunteers
-
Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Diagnostic criteria for obesity (BMI ≥ 28 kg/m²) and/or waist circumference ≥ 90 cm in adult males, ≥ 85 cm in adult females, or waist-to-hip ratio ≥ 0.9 in males and ≥ 0.85 in females; * Age 18-65 years; * Consent to undergo venous blood sampling and gastric emptying scintigraphy, with no contraindications to these procedures; * Consent to participate in this research project. Exclusion Criteria: * Diagnosed with secondary obesity, such as hypothyroidism, Cushing's syndrome, polycystic ovary syndrome, etc.; * Severe cardiovascular or cerebrovascular disease, rheumatic or immune-mediated disorders; * Severe metabolic disorders, such as diabetic ketoacidosis, hyperosmolar hyperglycaemic state, etc.; * Advanced malignant tumours; * History of medication known to affect glucose/lipid metabolism or gastric emptying rate, such as GLP-1 receptor agonists, glucocorticoids, antibiotics, anxiolytics or antidepressants; * Pregnancy or lactation; * Severe bleeding tendency or inability to undergo venous blood sampling; * Contraindications for gastric emptying scintigraphy, including pregnancy, lactation, severe gastrointestinal disorders such as acute gastrointestinal haemorrhage, intestinal obstruction or perforation, or allergy to components of the test meal; * Patients refusing gastric emptying scintigraphy, or refusal to sign the informed consent form; * Other circumstances deemed unsuitable for the study by the investigator.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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Ren Ji Hospital
Shanghai, Pudong New Area, China
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