Why are black African/Caribbean people at higher diabetes risk? stomach emptying may hold clues.
NCT ID NCT03864562
First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study compared how quickly the stomach empties a sugary drink in 30 white Europeans and 30 people of Black African or Caribbean descent. The goal was to understand why Black African/Caribbean people have a higher risk of type 2 diabetes. Researchers measured blood sugar, insulin, and gut hormones after the drink. The study is complete and aimed at gathering knowledge, not testing a new treatment.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- What this could lead to
- If successful, this study could reveal why people of Black African/Caribbean descent are more prone to type 2 diabetes, pointing toward future prevention strategies.
- What could go wrong
- This is a small, completed observational study with only 56 participants. It does not test a treatment, so it cannot directly lead to a cure or therapy.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Participants
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56 people
The number who actually took part.
- Started
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Mar 2019
- Finished
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Mar 2023
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
Who is studied
The study cohort will be recruited from the general population of England who live within commuting distance from the study site, and will incorporate those from the counties of Nottinghamshire, Derbyshire and Leicestershire
- Ages
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18 to 60 years
- Sex
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Anyone
- Healthy volunteers
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Accepted
You do not need to have the condition being studied to take part.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * White European or black African / Caribbean heritage * BMI \>18 kg/m2 * Ability to give written informed consent * English speaking Exclusion Criteria: * Any significant medical condition * Uncontrolled hypertension * Alcohol consumption \>14 units / week * Random blood Glucose concentration above 7.8mmol/l * Hemoglobin A1c (HbA1c) \>47mmol/mol (\>6.4%) * Use of regular medication, (oral contraceptive pill or antihypertensive medication are acceptable if use has been for \>6 months) * History of Irritable Bowel Syndrome, food intolerances or any gastrointestinal disorders * Previous bariatric surgery, or gastrointestinal surgery which may affect normal function (e.g. bowel resection)
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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David Greenfield Human Physiology Unit, University of Nottingham
Nottingham, Notts, NG72UH, United Kingdom
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