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New drug cocktail aims to shrink stomach tumors before surgery

NCT ID NCT04745988

First seen Apr 18, 2026 · Last updated May 18, 2026 · Updated 6 times

Summary

This study tests whether giving a combination of three drugs (lenvatinib, pembrolizumab, and FLOT chemotherapy) before and after surgery can help shrink or eliminate stomach cancer in 43 adults. Participants have early-stage stomach cancer that has not spread. The main goal is to see how many patients have very little or no cancer left after treatment. This is a phase 2 trial, meaning it checks safety and how well the treatment works.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • National Cancer Center Hospital East

    Kashiwa, Chiba, Japan

Conditions

Explore the condition pages connected to this study.