Knee pain study for runners never got off the ground
NCT ID NCT03314428
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study aimed to see if a 4-week running form retraining program could reduce knee pain and improve function in runners with mild to moderate knee osteoarthritis. It planned to measure changes in symptoms and knee joint loads. However, the study was withdrawn before any participants were enrolled, so no results are available.
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Study facts
What this study's own registry entry says, in plain language.
- Phase
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Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Expected to start
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Jul 2025
An estimate. Start dates often move.
- Expected to finish
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Jul 2026
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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40 years and older
- Sex
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Female participants only
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * TFOA of Grade 2 (mild) or 3 (moderate) on the Kellgren and Lawrence scale * report knee pain greater than or equal to 3/10 on a numerical pain rating scale (0-10) during most days of the previous month * run at least 10 km per week for a minimum of 6 months * declare being comfortable running on a treadmill for at least 30 minutes Exclusion Criteria: * history of traumatic knee injury * neurological or inflammatory arthritic condition * cardiovascular or cardiopulmonary disease preventing from safely performing moderate intensity running * presence of any lower limb condition affecting running (other than TFOA) * use of any oral or injected corticosteroids or viscosupplementation in the previous six months * regular use of non-steroidal anti-inflammatory drugs, analgesics or knee unloading bracing devices before, during or after running * non-English speaking
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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Robert H.N. Ho Research Centre
Vancouver, British Columbia, V5Z 1M9, Canada
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