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Can one pill before breast surgery cut the need for morphine?

NCT ID NCT07804784

Symptom relief Sponsor: Shaukat Khanum Memorial Cancer Hospital & Research Centre Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Sep 04, 2026 · Last updated Sep 04, 2026

Summary

This trial tests whether a single 600 mg dose of gabapentin, taken one hour before breast cancer surgery, reduces the amount of morphine needed for pain afterward. Sixty women scheduled for elective breast surgery will be randomly assigned to receive either gabapentin or a placebo pill. Researchers will measure total morphine use during recovery and watch for side effects like drowsiness, nausea, and vomiting. The goal is to see if this simple pre-treatment can improve pain control and lower opioid use.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
a single 600 mg oral dose of gabapentin given one hour before surgery
What this could lead to
If it works, a single pill before surgery could ease pain and cut the need for morphine, reducing opioid side effects.
What could go wrong
This is a small, early trial, and gabapentin may not reduce morphine use for everyone. It can also cause drowsiness, nausea, or vomiting.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

60 people

The number who actually took part.

Started

Jan 2026

Finished

Jun 2026

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 to 60 years

Sex

Female participants only

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: 1. Age between 18 to 60 years. 2. Female Gender 3. American Society of Anesthesiologists grade 1 and 2 patients. 4. Elective breast surgery 5. Admitted and day case surgeries Exclusion Criteria: 1. Patients allergic to gabapentin 2. Patients refusal. 3. Patients having a history of chronic pain. 4. Patients already using opioids for pain control

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Conditions

The condition(s) this trial relates to.

breast cancer breast neoplasm Pain

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Breast cancer surgery pain

Contacts and locations

Locations

  • Shaukat Khanum Memorial Cancer Hospital and Research Centre

    Lahore, Punjab Province, 5400, Pakistan

More trials for these conditions

Other studies related to the condition(s) this trial covers.