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New drug combo aims to boost stem cell transplant success in leukemia

NCT ID NCT07232953

First seen Nov 18, 2025 · Last updated May 21, 2026 · Updated 19 times

Summary

This study tests a combination of two chemotherapy drugs (fludarabine and treosulfan) given before a stem cell transplant in adults aged 40-65 with acute myeloid leukemia (AML) in remission. The goal is to see if this approach improves the chance of staying leukemia-free for at least one year. About 82 participants will receive the treatment and be monitored for safety and effectiveness.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • ASST degli Spedali Civili di Brescia

    Brescia, Lombardy, 25123, Italy

  • Azienda Ospedaliera S. Croce e Carle

    Cuneo, Piedmont, 12100, Italy

  • Azienda Ospedaliera Universitaria Integrata Verona

    Verona, Veneto, 37126, Italy

  • Azienda Ospedaliera Universitaria di Modena

    Modena, Emilia-Romagna, 41124, Italy

  • Azienda Ospedaliera di Rilievo Nazionale Antonio Cardarelli

    Naples, Campania, 80131, Italy

  • Azienda Ospedaliero Universitaria Careggi

    Florence, Tuscany, 50134, Italy

  • Azienda Sanitaria Universitaria Friuli Centrale

    Udine, Friuli Venezia Giulia, 33100, Italy

  • Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico,

    Milan, Lombardy, 20122, Italy

  • Grande Ospedale Metropolitano "Bianco Melacrino Morelli"

    Reggio Calabria, Calabria, 89124, Italy

  • IRCCS Ospedale San Raffaele

    Milan, Lombardy, 20132, Italy

  • Ospedale C e G Mazzoni

    Ascoli Piceno, The Marches, 63100, Italy

  • Ospedale dell'Angelo

    Mestre, Veneto, 30174, Italy

  • Ospedali Riuniti di Ancona

    Ancona, The Marches, 60126, Italy

Conditions

Explore the condition pages connected to this study.