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New cream aims to tame burn scars – trial underway

NCT ID NCT06807021

First seen Sep 30, 2025 · Last updated Jun 19, 2026 · Updated 34 times

Summary

This study tests a cream containing FS2 (kynurenic acid) to see if it can reduce scarring in burn patients who need skin grafts. About 70 people aged 12 to 65 will apply the cream or a placebo to both the graft and donor sites for 90 days. The goal is to check safety and whether scars look better with FS2.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Centre for Burn Research - Hamilton Health Sciences

    RECRUITING

    Hamilton, Ontario, L8L 2X2, Canada

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

    Contact

  • University of Alberta, Division of Plastic Surgery

    RECRUITING

    Edmonton, Alberta, T6G 2B7, Canada

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

FS2 (kynurenic acid) cream

What this could lead to

If it works, this could offer a simple cream to reduce scarring after burn surgery, improving appearance and skin function.

What could go wrong

This is an early-to-mid stage trial with only 70 participants. The cream may not reduce scars better than the control, and results may not apply to all burn types.

Conditions

The condition(s) this trial relates to.

burn severe cutaneous adverse reaction

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.