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New drug combo aims to stall colorectal cancer in patients Who've run out of options

NCT ID NCT06992258

First seen Jan 03, 2026 · Last updated May 23, 2026 · Updated 26 times

Summary

This study tests whether adding TAS-102 to fruquintinib helps people with advanced colorectal cancer live longer without their disease getting worse. About 120 adults whose cancer has not responded to standard treatments will be randomly assigned to receive either the drug combo or fruquintinib alone. The goal is to see if the combination delays cancer growth better than the single drug.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Inova Schar Cancer

    RECRUITING

    Fairfax, Virginia, 22031, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Mays Cancer Center at University of Texas Health at San Antonio

    RECRUITING

    San Antonio, Texas, 78229, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Mount Sinai Cancer Research Program

    RECRUITING

    Miami Beach, Florida, 33140, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • NYU Langone Health

    RECRUITING

    New York, New York, 10016, United States

    Contact Email: •••••@•••••

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Orlando Health Cancer Institute

    RECRUITING

    Orlando, Florida, 32806, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Rutgers Cancer Institute

    RECRUITING

    New Brunswick, New Jersey, 08903, United States

    Contact Email: •••••@•••••

  • UPenn Lancaster-Ann B. Barshinger Cancer Institute

    RECRUITING

    Lancaster, Pennsylvania, 17601, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Vanderbilt University Medical Center

    RECRUITING

    Nashville, Tennessee, 37232, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Yale University

    RECRUITING

    New Haven, Connecticut, 06520, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

Conditions

Explore the condition pages connected to this study.