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New combo therapy offers hope for hard-to-treat colorectal cancer patients

NCT ID NCT05954429

First seen Jan 23, 2026 · Last updated Jun 17, 2026 · Updated 26 times

Summary

This study tests a combination of two drugs, fruquintinib and serplulimab, in people with advanced colorectal cancer that has spread to places other than just the liver and has not responded to standard treatments. The goal is to see if this combination can shrink tumors or slow the disease. About 50 adults will take part, and researchers will also look at blood and tumor markers to understand who benefits most.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • Fudan University Shanghai Cancer Center

    NOT_YET_RECRUITING

    Shanghai, Shanghai Municipality, 200000, China

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Fudan University Shanghai Cancer Center

    RECRUITING

    Shanghai, Shanghai Municipality, 200032, China

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact Phone: •••-•••-•••• Email: •••••@•••••

Conditions

The condition(s) this trial relates to.

colorectal cancer colorectal neoplasm

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.