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Nerve block before shoulder injection may ease frozen shoulder pain

NCT ID NCT07380087

Symptom relief Sponsor: Universidade do Porto Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting This study
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

Frozen shoulder causes pain and stiffness. A common treatment called hydrodistension injects fluid into the shoulder joint to stretch it, but it can be painful. This study tests whether giving a nerve block first can reduce that pain and improve results. Fifty adults with frozen shoulder will be randomly assigned to get hydrodistension alone or with a nerve block, and their pain and mobility will be tracked for three months.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
suprascapular nerve block with local anesthetic
What this could lead to
If it works, this could make a common frozen shoulder treatment less painful and more effective, improving comfort and recovery.
What could go wrong
This is a small, early-stage trial with only 50 participants. The nerve block may not reduce pain enough to matter, and results may not apply to everyone.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

About 50 people

The number the study aims to enrol. It can still change while the study runs.

Expected to start

Mar 2026

An estimate. Start dates often move.

Expected to finish

Jul 2028

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 years and older

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria * Adults aged 18 years or older * Clinical diagnosis of adhesive capsulitis of the shoulder * Persistent pain and functional limitation despite initial conservative treatment * Ability to understand study procedures * Ability to provide written informed consent Exclusion Criteria * Known allergy or hypersensitivity to ropivacaine or methylprednisolone * Active infection (local or systemic) * Uncontrolled coagulopathy or ongoing therapeutic anticoagulation * Recent surgery of the affected shoulder * Neurological disease affecting the upper limb * Pregnancy

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Conditions

The condition(s) this trial relates to.

agnosia bursitis frozen shoulder Shoulder Pain

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Adhesive capsulitis Adhesive capsulitis of unspecified shoulder Adhesive capsulitis, shoulder Frozen shoulder Shoulder pain Shoulder stiffness

How to take part

Only the study team decides who joins. These are the ways to reach them.

  1. The places running it

    1 site. The list below names each one and where it is.

  2. The official record

    ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.

    Open the record ↗

  3. A doctor treating you

    A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.

Contacts and locations

Locations

  • Unidade Local de Saude São João, EPE

    Porto, Porto District, 4200-319, Portugal

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