New study reveals hidden hormone clues in rare nerve disease
NCT ID NCT07123142
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This pilot study explored whether people with Friedreich's ataxia (FA) have problems making certain hormones, like cortisol and testosterone. Researchers measured hormone levels in blood samples from 11 FA patients and 15 healthy volunteers. The goal was to better understand how FA affects the body beyond movement problems, which could lead to better care in the future.
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Study facts
What this study's own registry entry says, in plain language.
- Participants
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25 people
The number who actually took part.
- Started
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May 2025
- Finished
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Nov 2025
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
Who is studied
This study includes patients diagnosed with Friedreich's ataxia (FRDA) aged 7 to 33 years and age- and sex-matched healthy controls. All participants are followed in pediatric and adult endocrinology outpatient clinics. The study group consists of 11 FRDA patients (3 females, 8 males), and the control group consists of 15 healthy individuals (5 females, 10 males). Both prepubertal and pubertal subjects are included.
- Ages
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Children (under 18), adults (18 to 64) and older adults (65 and over)
- Sex
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Anyone
- Healthy volunteers
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Accepted
You do not need to have the condition being studied to take part.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria (FA Group): * Genetically confirmed Friedreich's Ataxia diagnosis * Signed informed consent (parents and/or participants depending on age) Inclusion Criteria (Control Group): * Healthy individuals with no known chronic or endocrine disease * Age- and sex-matched to FA patients * Signed informed consent
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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Istanbul University
Istanbul, 34093, Turkey (Türkiye)