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Sound waves to soothe PTSD? new trial tests ultrasound on the brain

NCT ID NCT06820138

First seen Feb 02, 2026

Summary

This phase 2 trial tests whether low intensity focused ultrasound, aimed at a deep brain region called the amygdala, can ease PTSD symptoms in 60 veterans. The treatment is non-invasive and uses sound waves similar to diagnostic ultrasound. Researchers will measure symptom changes and daily functioning over one month.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Providence VA Medical Center, Providence, RI

    Providence, Rhode Island, 02908-4734, United States

    Contact Email: •••••@•••••

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

low intensity focused ultrasound (Brainsonix Pulsar device)

What this could lead to

If it works, this could offer a new, non-invasive way to reduce PTSD symptoms and improve daily functioning for veterans.

What could go wrong

This is an early phase 2 trial with only 60 people, so results may not apply to everyone. The effects may be small or short-lived, and some participants may receive a sham treatment.

Conditions

The condition(s) this trial relates to.

post-traumatic stress disorder

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.