Den här översättningen är inte klar ännu. Den här sidan är just nu på engelska.

Gå till den engelska sidan

Cure My Disease

Don't miss your cure!

 Log in / Sign up

Drug access bridge: study offers continued treatment for solid tumor patients

NCT ID NCT05203172

Disease control Sponsor: Pfizer Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now This study
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study gives people who are already benefiting from the cancer drugs encorafenib and/or binimetinib in earlier trials continued access to these medicines for up to 5 years. It includes safety monitoring and is open to about 46 participants whose doctors confirm they are still gaining benefit. The goal is to keep providing treatment and track any side effects.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Phase 4

Runs after approval, following long-term safety and how well the treatment works in everyday use.

Participants

About 46 people

The number the study aims to enrol. It can still change while the study runs.

Started

Jul 2022

Expected to finish

Jul 2029

An estimate. End dates often move.

Lead sponsor

A company

The lead sponsor is a pharmaceutical, biotech, or medical-device company.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 years and older

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Any participant who is receiving study intervention and deriving clinical benefit (as determined by the principal investigator) in an encorafenib/binimetinib Parent Study, with no ongoing NCI CTCAE version 4.03 Grade ≥3 or intolerable Grade 2 AEs considered to be related to study treatment. * Participants must agree to follow the reproductive criteria as outlined in the applicable Encorafenib/Binimetinib Continuation Sub-Study Protocol. Exclusion Criteria: * Any medical reason that, in the opinion of the investigator or sponsor, precludes the participant from inclusion in the study.

Get updates

Get notified about this study

Sign up to get updates when this study changes or when new studies for Solid tumor are added.

Vår säkerhetsrekommendation!

Genom att skicka in godkänner du våra Användarvillkor

Conditions

The condition(s) this trial relates to.

neoplasm

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Solid tumors

How to take part

Only the study team decides who joins. These are the ways to reach them.

  1. The places running it

    57 sites in 15 countries. The list below names each one and where it is.

  2. The official record

    ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.

    Open the record ↗

  3. A doctor treating you

    A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.

Contacts and locations

Locations

  • BP - A Beneficencia Portuguesa de São Paulo

    RECRUITING

    São Paulo, São Paulo, 01321-001, Brazil

  • Barnes-Jewish Hospital

    RECRUITING

    St Louis, Missouri, 63110, United States

  • CHUAC-Hospital Teresa Herrera

    RECRUITING

    A Coruña, A Coruña [LA Coruña], 15006, Spain

  • Charité Universitaetsmedizin Berlin - Campus Mitte

    RECRUITING

    Berlin, 10117, Germany

  • Debreceni Egyetem Klinikai Kozpont

    RECRUITING

    Debrecen, 4032, Hungary

  • Duke Cancer Center

    RECRUITING

    Durham, North Carolina, 27710, United States

  • Emory University Hospital

    RECRUITING

    Atlanta, Georgia, 30322, United States

  • Emory University Hospital Midtown

    RECRUITING

    Atlanta, Georgia, 30308, United States

  • Fed State Budgetary Inst "N.N. Blokhin Med Center of Oncology" MHRF

    RECRUITING

    Moscow, 115478, Russia

  • Fundação Pio XII - Hospital de Câncer de Barretos

    RECRUITING

    Barretos, São Paulo, 14.780-070, Brazil

  • Gustave Roussy

    ACTIVE_NOT_RECRUITING

    Villejuif, Val-de-marne, 94800, France

  • H.R.U Málaga - Hospital General

    RECRUITING

    Málaga, 29011, Spain

  • HealthPartners Cancer Research Center

    RECRUITING

    Saint Paul, Minnesota, 55101, United States

  • Hopital Claude Huriez - CHU de Lille

    ACTIVE_NOT_RECRUITING

    Lille, NORD, 59037, France

  • Hospital Clinic de Barcelona

    RECRUITING

    Barcelona, Catalunya [cataluña], 08008, Spain

  • Hospital Clínic de Barcelona

    RECRUITING

    Barcelona, Catalunya [cataluña], 08036, Spain

  • Hospital Regional Universitario de Malaga

    RECRUITING

    Málaga, 29010, Spain

  • Hospital Universitari Vall d'Hebron

    RECRUITING

    Barcelona, Barcelona [barcelona], 08035, Spain

  • Hospital Universitari Vall d'Hebron

    RECRUITING

    Barcelona, 08035, Spain

  • Hospital Universitario Arnau de Vilanova de Lleida

    RECRUITING

    Lleida, Lleida [lérida], 25198, Spain

  • Hospital Universitario Central de Asturias

    RECRUITING

    Oviedo, 33011, Spain

  • Hospital Universitario HM Sanchinarro

    RECRUITING

    Madrid, 28050, Spain

  • Hospital Universitario Puerta de Hierro Majadahonda

    RECRUITING

    Majadahonda, Madrid, Comunidad de, 28222, Spain

  • IRCCS Azienda Ospedaliero-Universitaria di Bologna, Policlinico di Sant'Orsola

    RECRUITING

    Bologna, 40138, Italy

  • Institut Català d'Oncologia (ICO) - Badalona

    RECRUITING

    Badalona, Barcelona [barcelona], 08916, Spain

  • Instituto Português de Oncologia de Lisboa Francisco Gentil

    RECRUITING

    Lisbon, Lisbon District, 1099-023, Portugal

  • Instituto Português de Oncologia do Porto Francisco Gentil, EPE

    RECRUITING

    Porto, 4200-072, Portugal

  • Instituto Tumori Giovanni Paolo II

    RECRUITING

    Bari, Apulia, 70124, Italy

  • Investigational Chemotherapy Service

    RECRUITING

    Durham, North Carolina, 27710, United States

  • Investigational Drug Service Emory University Clinic

    RECRUITING

    Atlanta, Georgia, 30322, United States

  • Isala, locatie Zwolle

    ACTIVE_NOT_RECRUITING

    Zwolle, 8025 AB, Netherlands

  • Istituto Europeo di Oncologia IRCCS

    ACTIVE_NOT_RECRUITING

    Milan, 20141, Italy

  • Istituto Nazionale Tumori IRCCS Fondazione Pascale

    RECRUITING

    Naples, 80131, Italy

  • Istituto Nazionale Tumori Regina Elena

    RECRUITING

    Rome, ROMA, 00144, Italy

  • Istituto Oncologico Veneto IRCCS

    RECRUITING

    Padova, Veneto, 35128, Italy

  • Istituto di Candiolo IRCCS - Fondazione del Piemonte per l'Oncologia

    RECRUITING

    Candiolo, Torino, 10060, Italy

  • Jewish General Hospital

    RECRUITING

    Montreal, Quebec, H3T 1E2, Canada

  • Lancashire Teaching Hospitals NHS Foundation Trust - Royal Preston Hospital

    RECRUITING

    Preston, Lancashire, PR2 9HT, United Kingdom

  • Liga Norte Riograndense Contra o Câncer

    RECRUITING

    Natal, Rio Grande do Norte, 59062-000, Brazil

  • MSK Basking Ridge

    ACTIVE_NOT_RECRUITING

    Basking Ridge, New Jersey, 07920, United States

  • Massachusetts General Hospital

    RECRUITING

    Boston, Massachusetts, 02114, United States

  • Memorial Sloan Kettering Cancer Center

    ACTIVE_NOT_RECRUITING

    New York, New York, 10065, United States

  • N.N.Petrov Research Institute of Oncology

    RECRUITING

    Saint Petersburg, Sankt-Peterburg, 197758, Russia

  • N.N.Petrov Research Institute of Oncology

    RECRUITING

    Saint Petersburg, 197758, Russia

  • Narodny onkologicky ustav

    ACTIVE_NOT_RECRUITING

    Bratislava, Bratislava Region, 833 10, Slovakia

  • Nederlands Kanker Instituut - Antoni van Leeuwenhoek (NKI-AVL)

    RECRUITING

    Amsterdam, North Holland, 1066 CX, Netherlands

  • ONCOSITE - Centro de Pesquisa Clinica em Oncologia

    RECRUITING

    Ijuí, Rio Grande do Sul, 98700-000, Brazil

  • Otto-von-Guericke-Universitat Magdeburg

    ACTIVE_NOT_RECRUITING

    Magdeburg, Saxony-Anhalt, 39120, Germany

  • Peter MacCallum Cancer Centre

    RECRUITING

    Melbourne, Victoria, 3000, Australia

  • Princess Margaret Cancer Centre

    RECRUITING

    Toronto, Ontario, M5G 2M9, Canada

  • Radboudumc

    RECRUITING

    Nijmegen, Gelderland, 6525 GA, Netherlands

  • Rambam Health Care Campus

    RECRUITING

    Haifa, Northern District, 3109601, Israel

  • Real e Benemerita Associacao Portuguesa de Beneficencia

    RECRUITING

    São Paulo, São Paulo, 01323-030, Brazil

  • Regions Hospital Pharmacy

    RECRUITING

    Saint Paul, Minnesota, 55101, United States

  • Rockefeller Outpatient Pavilion (53rd Street)

    ACTIVE_NOT_RECRUITING

    New York, New York, 10022, United States

  • Samsung Medical Center

    RECRUITING

    Seoul, Seoul-teukbyeolsi [seoul], 06351, South Korea

  • Seoul National University Hospital

    RECRUITING

    Seoul, Seoul-teukbyeolsi [seoul], 03080, South Korea

  • Severance Hospital, Yonsei University Health System

    RECRUITING

    Seoul, Seoul-teukbyeolsi [seoul], 03722, South Korea

  • Siteman Cancer Center

    RECRUITING

    St Louis, Missouri, 63108, United States

  • St. Joseph's Hospital and Medical Center

    RECRUITING

    Phoenix, Arizona, 85004, United States

  • St. Joseph's Hospital and Medical Center

    RECRUITING

    Phoenix, Arizona, 85013, United States

  • Universitaetsklinikum Tuebingen

    ACTIVE_NOT_RECRUITING

    Tübingen, Baden-Wurttemberg, 72076, Germany

  • University Health Network

    RECRUITING

    Toronto, Ontario, M5G 2C4, Canada

  • Vseobecna fakultni nemocnice v Praze

    RECRUITING

    Prague, Praha 2, 12808, Czechia

  • Washington University

    RECRUITING

    St Louis, Missouri, 63110, United States

  • Washington University School of Medicine

    RECRUITING

    St Louis, Missouri, 63110, United States

  • Winship Cancer Institute of Emory University

    RECRUITING

    Atlanta, Georgia, 30322, United States

More trials for these conditions

Other studies related to the condition(s) this trial covers.