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New antibody drug tested in patients with relapsed blood cancers

NCT ID NCT04681105

First seen Feb 01, 2026 · Last updated Jun 18, 2026 · Updated 15 times

Summary

This early-stage trial tested the safety and best dose of flotetuzumab, an antibody drug, in 13 patients with advanced blood cancers that had come back or stopped responding to treatment. The drug works by blocking cancer cell growth. The main goal was to see what side effects occur and how severe they are.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • City of Hope Medical Center

    Duarte, California, 91010, United States

Conditions

The condition(s) this trial relates to.

acute leukemia acute leukemia of ambiguous lineage acute lymphoblastic leukemia B-cell acute lymphoblastic leukemia Blastic Plasmacytoid Dendritic Cell Neoplasm Burkitt lymphoma CD4+/CD56+ hematodermic neoplasm chronic myelogenous leukemia, BCR-ABL1 positive hairy cell leukemia hematopoietic and lymphoid system neoplasm Hodgkins lymphoma Leukemia, Myelogenous, Chronic, BCR-ABL Positive Mastocytosis, Systemic Precursor T-Cell Lymphoblastic Leukemia-Lymphoma refractory hairy cell leukemia refractory hematologic cancer refractory precursor T-lymphoblastic lymphoma/leukemia systemic mastocytosis T-cell acute lymphoblastic leukemia

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.