Soft brain probe tested in humans for first time

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria * Adults 18-80 years of age at the time of providing informed consent * Capable of providing written informed consent to participate * Willing to commit to the study evaluations and visit schedule * Undergoing a planned surgery for brain tissue resection of either a tumor or of a epileptogenic lesion * Adequate hepatic, renal, cardiac, and hematologic function according to the following laboratory test criteria: * Absolute neutrophil count ≥ 1,500/mm3 * Platelet count ≥ 100,000/mm3 * Bilirubin ≤ 1.5 mg/dL * AST and ALT ≤ 2.5 times upper limit of normal * Creatinine ≤ 1.5 mg/dL * Signs of previous or current ischemic cardiac disease or arrhythmia per electrocardiogram assessment * Females of childbearing potential must have a negative serum pregnancy test and agree to use birth control measures during study treatment and for 3 months after its completion * Must not be pregnant or nursing at study entry * Women/men of reproductive potential must have agreed to use an effective contraceptive method Exclusion Criteria * Substance abuse, according to the criteria of the Diagnostic and Statistical Manual of Mental Disorders, 5th edition (DSM-5) * Allergy to any study materials * Presence of any powered implantable medical device or any medical device implanted in the brain * Weakened immune system due to presence of poorly controlled chronic diseases such as human immunodeficiency virus (seropositive for HIV 1 or 2), decompensated diabetes, decompensated chronic kidney disease, decompensated liver disease, intake of immunosuppressive medications such as high-dose corticosteroids, or a previous diagnosis of congenital or acquired immunodeficiency * Exposure to any type of chemotherapy in the past 3 months * Radiation therapy in the surgical area within the last year * Delay to the base operation creates additional risk for the patient due to uncontrolled elevated ICP or emergency surgery * Active infection, bleeding, or hematoma * Patients with previous resection surgery in the planned surgical area * Previous stroke in the affected tissue * Currently high levels of inflammation as indicated by ESR, CRP, or PCT blood test * Any concurrent medical condition or disease (e.g. uncontrolled active hypertension, uncontrolled active diabetes, or active systemic infection) that is likely to interfere with study procedures. * Uncontrolled active infection requiring parenteral antibiotics, antivirals, or antifungals within 1 week prior to the planned neurosurgical intervention. Patients on prophylactic antibiotics or with a controlled infection within 1 week prior to the planned neurosurgical intervention are acceptable. * Any active, serious psychiatric, medical, or other conditions/situations that, in the opinion of the Investigator, could interfere with treatment, compliance, or the ability to give informed consent. * Any other psychological, family or geographic problem that may make compliance with the study protocol difficult. * Life expectancy of less than 3 months. * Major surgery within 4 weeks prior to planned neurosurgical intervention