Den här översättningen är inte klar ännu. Den här sidan är just nu på engelska.

Gå till den engelska sidan

Cure My Disease

Don't miss your cure!

 Log in / Sign up

Could a prostate drug stop shoulder infections before they start?

NCT ID NCT07731802

Disease control Sponsor: University of Washington Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting This study
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jul 28, 2026 · Last updated Jul 29, 2026 · Updated 1 time

Summary

This trial tests whether finasteride, a drug that blocks testosterone production, can reduce levels of Cutibacterium acnes bacteria on the skin. High testosterone is linked to more of this bacteria, which can cause serious infections during shoulder replacement surgery. Healthy men aged 18 to 65 will take either finasteride or a placebo daily for two weeks, and researchers will measure changes in skin bacteria and blood testosterone levels.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
finasteride 1 mg taken daily for two weeks
What this could lead to
If it works, this could point toward a simple, short-term way to reduce infection risk before shoulder replacement surgery.
What could go wrong
This is a small, early-phase trial with only 40 men. It tests a surrogate marker (skin bacteria), not actual infection rates, so success here may not prevent infections in practice.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Phase 4

Runs after approval, following long-term safety and how well the treatment works in everyday use.

Participants

About 40 people

The number the study aims to enrol. It can still change while the study runs.

Expected to start

Aug 2026

An estimate. Start dates often move.

Expected to finish

Aug 2027

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 to 65 years

Sex

Male participants only

Healthy volunteers

Accepted

You do not need to have the condition being studied to take part.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion We will include the group most impacted by PJI * Adult males * Age between 18 and 65 Exclusion * History of cryptorchidism, hypospadias, or other congenital abnormality of male reproductive tract * Female sex * Age younger than 18 or older than 65 * Current use of Finasteride or other 5-alpha reductase inhibitors * Current use of hormone replacement medications such as testosterone * Recent antibiotic use within 3 months * Have had a negative reaction to oral Finasteride before * Recent use of acne treatment within 3 months * Self-report very sensitive skin * Allergic to chlorhexidine or isopropyl alcohol * Have open wounds on both shoulders

Get updates

Get notified about this study

Sign up to get updates when this study changes or when new studies for Cutibacterium acnes are added.

Vår säkerhetsrekommendation!

Genom att skicka in godkänner du våra Användarvillkor

Conditions

The condition(s) this trial relates to.

periprosthetic joint infection

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Cutibacterium acnes Dihydrotestosterone Periprosthetic joint infection (PJI)

How to take part

Only the study team decides who joins. These are the ways to reach them.

  1. The official record

    ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.

    Open the record ↗

  2. A doctor treating you

    A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.

More trials for these conditions

Other studies related to the condition(s) this trial covers.