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Cash for clean blood: new trial offers money to help liver patients quit alcohol

NCT ID NCT07465588

Disease control Sponsor: Massachusetts General Hospital Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting This study
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tests whether giving financial rewards based on a blood test can help people with alcohol-related liver disease stop or reduce drinking. The blood test detects alcohol use over the past month. 90 adults will be randomly assigned to either a rewards group that gets escalating payments for reduced drinking or a monitoring group that gets fixed payments. The goal is to see if the rewards program improves abstinence and reduces alcohol use over 12 and 24 weeks.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

About 90 people

The number the study aims to enrol. It can still change while the study runs.

Expected to start

Aug 2026

An estimate. Start dates often move.

Expected to finish

Jun 2028

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 years and older

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Adults aged 18 years or older * Diagnosis of alcohol use disorder based on DSM 5 criteria * Diagnosis of alcohol associated liver disease or clinically suspected alcohol related liver injury * Evidence of recent alcohol use or at risk for alcohol relapse * Receiving care in hepatology or liver disease clinic at the participating institution * Willingness to undergo serial phosphatidylethanol (PEth) testing using dried blood spot samples * Ability to provide informed consent * Willingness to participate in the contingency management intervention and follow study procedures Exclusion Criteria: * Severe cognitive impairment or medical condition that prevents participation in study procedures * Active psychosis or severe psychiatric instability that would interfere with participation * Current enrollment in another contingency management program targeting alcohol use * Medical instability requiring hospitalization at the time of enrollment * Inability to communicate in English (if study materials are only available in English) * Any condition that, in the opinion of the investigators, would make participation unsafe or interfere with completion of the study

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Conditions

The condition(s) this trial relates to.

Alcohol Abstinence alcohol abuse alcoholic hepatitis alcoholic liver cirrhosis alcoholic liver disease liver disorder

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Alcohol use disorder Alcohol-associated hepatitis Alcohol-associated liver disease Liver cirrhosis, alcoholic

How to take part

Only the study team decides who joins. These are the ways to reach them.

  1. The official record

    ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.

    Open the record ↗

  2. A doctor treating you

    A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.

More trials for these conditions

Other studies related to the condition(s) this trial covers.