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Fiber before surgery: could a diet change improve colon cancer outcomes?

NCT ID NCT06212817

Disease control Sponsor: Wageningen University Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 26, 2026 · Last updated Sep 01, 2026 · Updated 3 times

Summary

This study looks at whether it's possible to increase fiber intake in people with colorectal cancer before they have surgery. Researchers will compare personalized digital dietary advice, a dried vegetable product, and usual diet in 54 participants. The goal is to see if fiber intake changes and if it affects bowel habits and gut symptoms.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
dietary fiber (via personalized advice or dried vegetable product)
What this could lead to
If successful, this could show that boosting fiber before surgery is practical and may help with bowel function and symptoms.
What could go wrong
This is a small feasibility study, not designed to prove clinical benefit. Results may not change standard care.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

54 people

The number who actually took part.

Started

Apr 2024

Finished

Aug 2026

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 years and older

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Age ≥18 years; * Being diagnosed with CRC and planned to undergo elective CRC resection; Exclusion Criteria: * Previously have had a large abdominal resection, excluding appendectomy and cholecystectomy; * Diagnosed with Crohn's disease, Ulcerative Colitis, Celiac Disease; * Currently having a stoma; * Known allergic reactions to plants from the Asteraceae (Compositae) family (e.g., lettuce, daisies, sunflowers, artichokes, sage, tarragon, chamomile, chicory etc.); * Currently following a strict diet and unwilling or unable to change (e.g., gluten free or ketogenic diet); * Currently using fiber supplements, prebiotics and/or probiotics and unwilling to stop using these for the duration of the intervention; * Having a habitual dietary fiber intake \>30 g/day for women and \>40 g/day for men, measured with a food frequency questionnaire; * Dementia or other cognitive disabilities that makes it impossible to fill out questionnaires correctly; * Illiteracy (inability to read and understand Dutch).

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Conditions

The condition(s) this trial relates to.

colorectal cancer colorectal neoplasm Postoperative Complications

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Colorectal cancer

Contacts and locations

Locations

  • Meander Medisch Centrum

    Amersfoort, Utrecht, Netherlands

  • Rijnstate

    Arnhem, Gelderland, Netherlands

  • Ziekenhuis Gelderse Vallei

    Ede, Gelderland, Netherlands

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