Hope for young cancer survivors: ovarian tissue freezing may preserve fertility
NCT ID NCT03180827
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study offers girls and young teens facing strong cancer treatments the chance to freeze a piece of their ovary before therapy begins. The goal is to help preserve their ability to have biological children later in life. Around 100 participants will undergo a safe procedure to collect and store ovarian tissue. Researchers will track safety and long-term outcomes to improve future fertility options.
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Study facts
What this study's own registry entry says, in plain language.
- Phase
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Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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About 100 people
The number the study aims to enrol. It can still change while the study runs.
- Started
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Jun 2015
- Expected to finish
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Jan 2100
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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2 months to 18 years
- Sex
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Female participants only
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
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Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Pediatric pre ou peripubertal patient aged 2 months and older * Patient presenting high risk of infertility because of gonadotoxic treatments (i.e. high dose of alkylating agents, ovarian irradiation, total body irradiation) * Multidisciplinary team consensus in favour to proposition to cryopreserve ovarian tissue. Exclusion Criteria: * Patient under the age of 2 months * Refusal of the patient and/or her parents * Treatments that are not highly gonadotoxic
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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CHUV
Lausanne, Switzerland
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Geneva University Hospitals
Geneva, 1211, Switzerland
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Other studies related to the condition(s) this trial covers.
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