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Scientists examine bone tissue to uncover causes of hip joint decay

NCT ID NCT02733900

Knowledge-focused Sponsor: Lille Catholic University Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study looked at bone tissue from 34 men who had hip replacement surgery due to femoral head necrosis (bone death in the hip joint). Researchers used advanced imaging and spectroscopy to identify changes in bone structure and composition. The goal was to better understand what causes the condition and how it progresses, not to test a new treatment.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

34 people

The number who actually took part.

Started

Feb 2016

Finished

Dec 2020

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

25 to 70 years

Sex

Male participants only

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria for experimental group: * Men * Patients aged from 25 to 70 years * Patient with an aseptic osteonecrosis of the femoral head established by medical Imaging (CT-scan, MRI or radiography) * FICAT stage 3 or 4 * osteonecrosis etiologies : alcohol, corticosteroid therapy, idiopathic * Surgical indication of hip prosthesis determined Inclusion Criteria for control group: * Men * Patients aged from 40 to 70 years * Patient with a primitive coxarthrosis * Surgical indication of hip prosthesis determined Exclusion Criteria for the 2 groups: * Other causes of osteonecrosis (coagulopathy, barotrauma, trauma) * Prior fracture of the upper extremity of the femur * Prior cancer and hematological malignancies with bone locations * Prior debilitating bone diseases * Patient refusal to participate in the study * Patient who isn't affiliated to a social security regimen

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Conditions

The condition(s) this trial relates to.

avascular necrosis avascular necrosis of femoral head, primary, 1 familial avascular necrosis of femoral head osteoarthritis, hip

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Femur head necrosis

Contacts and locations

Locations

  • Hospital Group of the Catholic Institute of Lille

    Lomme, 59462, France

  • Hospital Salengro CHU Lille

    Lille, 59037, France

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