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New hip block could cut opioid use after surgery

NCT ID NCT04301687

Symptom relief Sponsor: Women's College Hospital Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting This study
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tests whether a targeted injection of numbing medicine around the hip joint can reduce pain and the need for opioid painkillers after hip replacement surgery. Half of the 95 participants will get the active nerve block, and half will get a placebo (salt water) injection. Neither the patients nor the doctors will know who got which treatment. The goal is to see if this simple procedure improves recovery and reduces opioid use.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
Ropivacaine (local anesthetic)
What this could lead to
If it works, this could offer a better way to manage pain after hip replacement, reducing the need for strong painkillers like opioids.
What could go wrong
This is a small, early-stage trial. The nerve block may not provide significant pain relief compared to placebo, and there are risks like infection or nerve damage, though rare.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

About 95 people

The number the study aims to enrol. It can still change while the study runs.

Expected to start

Dec 2026

An estimate. Start dates often move.

Expected to finish

Dec 2028

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 to 85 years

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * ASA I-III patients * Ages 18-60yrs * BMI ≤ 35 kg/m2 Exclusion Criteria: * Preexisting neurological deficits or peripheral neuropathy in the distribution of femoral, obturator, or lateral cutaneous nerves * Local infection * Contra-indication to regional anesthesia e.g. bleeding diathesis, coagulopathy * Chronic pain disorders * History of use of over 30mg oxycodone or equivalent per day * Contraindication to a component of multi-modal analgesia * Allergy to local anesthetics * History of significant psychiatric conditions that may affect patient assessment * Pregnancy * Inability to provide informed consent * Patient refusal of FAB * Revision arthroscopy surgeries

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As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Anesthesia, regional Femoral articular branch block Hip arthroplasty

How to take part

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  1. The official record

    ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.

    Open the record ↗

  2. A doctor treating you

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