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Brain scan breakthrough: spotting hidden brain inflammation

NCT ID NCT06019975

Diagnosis Sponsor: University of Milano Bicocca Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now This study
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study looks at whether a special brain scan called FDG-PET can help doctors diagnose autoimmune encephalitis, a condition where the immune system attacks the brain. Researchers will compare scans from 90 patients with the disease to scans from healthy people and those with Alzheimer's. The goal is to find a unique brain activity pattern that could lead to faster and more accurate diagnosis.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Participants

About 90 people

The number the study aims to enrol. It can still change while the study runs.

Started

Mar 2023

Expected to finish

Apr 2027

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Who is studied

Patients with autoimmune encephalitis admitted to the recruiting centers

Ages

Children (under 18), adults (18 to 64) and older adults (65 and over)

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Diagnosis of autoimmune encephalitis according to clinical criteria * Brain magnetic resonance imaging performed between clinical presentation and treatment * Cerebrospinal fluid analysis performed between clinical presentation and treatment * Brain FDG-PET performed between clinical presentation and treatment * Autoantibodies testing performed between clinical presentation and treatment Exclusion Criteria: * Refusal to give consent for the study

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Conditions

The condition(s) this trial relates to.

autoimmune disorder of the nervous system autoimmune encephalitis

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Autoimmune encephalitis

How to take part

Only the study team decides who joins. These are the ways to reach them.

  1. The places running it

    6 sites. The list below names each one and where it is.

  2. The official record

    ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.

    Open the record ↗

  3. A doctor treating you

    A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.

Contacts and locations

Locations

  • Azienda Sanitaria Universitaria Friuli Centrale

    NOT_YET_RECRUITING

    Udine, Friuli Venezia Giulia, Italy

  • Fondazione IRCCS Istituto Neurologico "Carlo Besta"

    NOT_YET_RECRUITING

    Milan, Milano, 20133, Italy

  • Fondazione IRCCS Mondino

    RECRUITING

    Pavia, Lombardy, Italy

  • Fondazione IRCCS San Gerardo dei Tintori

    RECRUITING

    Monza, Monza e Della Brianza, 20900, Italy

  • IRCCS Ospedale Policlinico San Martino

    NOT_YET_RECRUITING

    Genoa, Liguria, Italy

  • Ospedale San Paolo

    NOT_YET_RECRUITING

    Milan, Milano, 20142, Italy

More trials for these conditions

Other studies related to the condition(s) this trial covers.