Could skipping breakfast help fight uterine cancer?
NCT ID NCT07622901
First seen Jun 27, 2026 · Last updated Jul 15, 2026 · Updated 2 times
Summary
This study looks at whether it is safe for women with endometrial cancer to fast overnight before their surgery. Many women with this cancer have high blood sugar and inflammation, which may help the cancer grow. The study will check if fasting is doable and liked by patients, and if it improves health markers like blood sugar and insulin levels. About 42 women will take part.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Phase
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Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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About 42 people
The number the study aims to enrol. It can still change while the study runs.
- Started
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Feb 2026
- Expected to finish
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Feb 2028
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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18 years and older
- Sex
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Female participants only
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: 1. Women 18 years of age or older. 2. Able to provide consent. 3. Able to read/understand English, Spanish or Haitian Creole. 4. Have a diagnosis of Type I (low-grade) endometrial cancer at any stage, histologically confirmed prior to the start of the intervention. 5. Planned minimally invasive surgical treatment (laparoscopy or robotic approach to hysterectomy). 6. Approval to participate from treating oncologist, confirmed via email or in writing. 7. Eastern Cooperative Oncology Group (ECOG) Performance status grade 0-2. 8. Surgeries must be at one of the following institutions: 1. Sylvester Comprehensive Cancer Center 2. University of Miami Hospital (UHealth) Tower 9. Internet access on a smart phone, tablet, or computer. 10. Agree to be randomly assigned to any study group. Exclusion Criteria: 1. Women less than 18 years of age. 2. Unable to provide consent. 3. Unable to read/understand English or Spanish. 4. History of prior hysterectomy. 5. Any contraindication for prolonged overnight fasting of 13 hours or exercising as determined by a physician. 6. Engaging in structured fasting consistently (equal to or more than 50% of the time) for \>12 hours/night. 7. Presence of a severe medical or psychiatric condition or medication that would preclude participation of the study intervention, unstable cardiac disease. 8. Diagnosis of diabetes treated with insulin, metformin, sulfonylureas, or Glucagon-like peptide-1 (GLP-1) agonist medications. 9. Recent history of a clinical eating disorder as determined by self-report, medical history, or clinical judgement. Participants with a history of an eating disorder that is well-managed and in sustained remission may be eligible, subject to investigator discretion. 10. Women for whom definitive hysterectomy is not planned for treatment of their endometrial cancer.
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Genom att skicka in godkänner du våra Användarvillkor
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
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The places running it
1 site. The list below names each one and where it is.
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The official record
ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.
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A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
Contacts and locations
Locations
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University of Miami
RECRUITINGMiami, Florida, 33136, United States
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