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Wake up faster after colonoscopy: new study tests early sedation stop

NCT ID NCT07168135

Symptom relief Sponsor: American University of Beirut Medical Center Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing This study
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 24, 2026 · Last updated Jun 26, 2026 · Updated 1 time

Summary

This study tests whether stopping the sedative propofol right after the colonoscope reaches the end of the large intestine (cecum) helps patients recover their thinking and movement faster after the procedure. About 100 adults having routine colonoscopy will be randomly assigned to either stop propofol early or continue it as usual. The goal is to see if this change shortens recovery time without making the procedure uncomfortable.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
propofol
What this could lead to
If it works, this could lead to faster recovery after colonoscopy and lower sedation costs.
What could go wrong
This is a small, early-stage trial with only 100 participants. The change might not improve comfort or could cause discomfort during the procedure.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

100 people

The number who actually took part.

Started

May 2025

Expected to finish

Dec 2025

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 to 80 years

Sex

Anyone

Healthy volunteers

Accepted

You do not need to have the condition being studied to take part.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Age between 18 and 80 years. * Scheduled ambulatory elective screening or surveillance colonoscopy under MAC. Exclusion Criteria: * Medical contraindication to anesthesia (i.e., respiratory/cardiac/neurologic compromise, known allergy or adverse reaction to propofol, midazolam, lidocaine, or opiates, …) * History of ischemic or hemorrhagic cerebrovascular accident. * Baseline cognitive dysfunction (impaired memory, attention deficit, language disorders, …) - in other words, any dysfunction that prevents the subject from understanding the study protocol and/or completing the requested tests and assessments (e.g., playing the minigames, …) * Use of more than one psychoactive drug. * History of partial colectomy. * Unable to give consent.

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As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Cecal intubation success rate Colonoscopy Procedural sedation Propofol adverse reaction

Contacts and locations

Locations

  • The American University of Beirut Medical Center

    Beirut, 1107, Lebanon

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