New scan could help decide who benefits from heart surgery
NCT ID NCT07657650
First seen Jun 25, 2026 · Last updated Jul 02, 2026 · Updated 2 times
Summary
This study is testing whether a special type of imaging called FAPI can better predict how much heart function will improve after bypass surgery or stenting in people with ischemic heart failure. Researchers will follow 122 patients for 12 months, measuring changes in heart pumping ability and tracking major heart events. The goal is to see if FAPI imaging provides more useful information than current methods.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- What this could lead to
- If successful, this could give doctors a more reliable imaging test to decide which heart failure patients will benefit from bypass surgery or stenting.
- What could go wrong
- This is an observational study, not a treatment trial. The imaging method may not prove better than existing tests, and results may not change clinical practice.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Participants
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About 122 people
The number the study aims to enrol. It can still change while the study runs.
- Started
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Apr 2026
- Expected to finish
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Dec 2028
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
Who is studied
It meets the relevant standards for IHF as stipulated in the "2024 Chinese Guidelines for the Diagnosis and Treatment of Heart Failure", and has a clear history of ischemic heart disease (such as previous myocardial infarction, history of revascularization, or confirmed coronary artery lesions by coronary angiography), and the echocardiogram shows that LVEF is ≤ 40%.
- Ages
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18 years and older
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: ① Age ≥ 18 years; ② Meet the above-mentioned IHF diagnostic criteria; ③ Coronary angiography shows suitability for revascularization (PCI or CABG); ④ NYHA cardiac function classification is II-IV; ⑤ Sign the informed consent form. Exclusion Criteria: ① Heart failure caused by non-ischemic etiologies (such as dilated cardiomyopathy, valvular heart disease, myocarditis, etc.); ② Acute myocardial infarction occurred within the last 3 months; ③ Expected lifespan \< 1 year; ④ Complicated with other severe systemic diseases; ⑤ Has a history of tumors; ⑥ Has any conditions that are unsuitable for revascularization (such as uncorrectable coagulation dysfunction, active bleeding, etc.)
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
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The places running it
1 site. The list below names each one and where it is.
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The official record
ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.
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A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
Contacts and locations
Locations
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Beijing Chaoyang Hospital, Capital Medical University
RECRUITINGBeijing, 100020, China
More trials for these conditions
Other studies related to the condition(s) this trial covers.
- Rehab program shows promise in tracking blood flow recovery
- Stem cell injection during bypass surgery aims to repair damaged hearts
- Heart failure patients get RNA boost during bypass in first human test
- Stem cell patch aims to mend broken hearts in landmark trial
- Could your own bone marrow repair a failing heart?
- Lab-grown heart cells injected into failing hearts: a new hope?