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Can a 10-Week program shield kids from depression?

NCT ID NCT00183365

Prevention Sponsor: Children's Hospital of Philadelphia Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 2 times

Summary

This study tested a 10-week program called the Protecting Families Program (PFP) for depressed parents and their pre-teen children. The goal was to see if the program could prevent depression in the children. 42 families took part, with parents in treatment for depression. The program included group sessions for parents and cognitive behavioral therapy for the kids. Researchers measured child psychiatric symptoms, parenting skills, and family functioning.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
Protecting Families Program (PFP) - a 10-week behavioral program including parent skills training and child cognitive behavioral therapy
What this could lead to
If successful, this program could provide an effective way to prevent depression in children of depressed parents.
What could go wrong
This is a small, early-phase study with only 42 participants, so results may not apply to everyone. The program is intensive and may not work for all families.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Phase 1

The first testing in people. Mainly checks safety and dose, usually in a small group.

Participants

42 people

The number who actually took part.

Start date

Oct 2005

Finished

Nov 2009

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

9 years and older

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Parent is currently in treatment * Parent's primary DSM-IV diagnosis is major depressive disorder, dysthymia, or depression not otherwise specified * Parent's child lives with him/her at least part time Exclusion criteria: * Parent has a history or current diagnosis of any psychotic disorder or organic brain syndrome * Parent has history of bipolar or schizoaffective disorder * Parent's IQ is below 70 * Parent has any serious medical or neurological disorder or condition that may prevent weekly participation * Parent has chronic pain that may prevent weekly participation * Parent or child is currently suicidal to the extent that it will interfere with outpatient treatment * Parent has a current substance dependence * Child is currently seeking psychological treatment * Child is mentally retarded (determined by school and clinic records) * Child has a clinically severe psychiatric diagnosis

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Conditions

The condition(s) this trial relates to.

Depression depressive disorder dysthymic disorder major depressive disorder

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Depression

Contacts and locations

Locations

  • Center for Family Intervention Science; The Children's Hospital of Philadelphia

    Philadelphia, Pennsylvania, 19104, United States

More trials for these conditions

Other studies related to the condition(s) this trial covers.