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Scientists hunt for genetic clues in families prone to blood cancers

NCT ID NCT00039676

First seen Nov 01, 2025 · Last updated Jun 22, 2026 · Updated 32 times

Summary

This study looks at people and families who have a higher chance of developing blood or lymph node cancers, like leukemia or lymphoma. Researchers want to understand what causes this higher risk, including genetic and environmental factors. Participants provide medical history, blood or cheek cell samples, and may have additional tests at the NIH. The goal is to find clues that could lead to better prevention and early detection.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • NIH National Cancer Institute - Shady Grove

    Rockville, Maryland, 20850, United States

  • National Institutes of Health Clinical Center

    Bethesda, Maryland, 20892, United States

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

What this could lead to

If successful, this could identify genes and risk factors that lead to better screening and prevention strategies for blood cancers in high-risk families.

What could go wrong

This is an observational study, not a treatment trial. It may not directly benefit participants, and findings may take years to translate into clinical practice.

Conditions

The condition(s) this trial relates to.

B-cell chronic lymphocytic leukemia Hodgkins lymphoma leukemia lymphoma non-Hodgkin lymphoma Waldenstrom macroglobulinemia

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.