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Massive database aims to unlock secrets of facial birth defects

NCT ID NCT07422454

First seen Feb 24, 2026

Summary

This study is creating a large database of genetic and physical information from 3100 children with craniofacial abnormalities, such as craniosynostosis and Pierre Robin sequence. Researchers will analyze this data to understand why these conditions vary so much from person to person. The goal is to improve diagnosis, predict outcomes, and design personalized treatment plans.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • Pr Stanislas Lyonnet

    RECRUITING

    Paris, France

    Contact Phone: •••-•••-•••• Email: •••••@•••••

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

What this could lead to

If successful, this could lead to better diagnosis and personalized treatment plans for children with craniofacial abnormalities.

What could go wrong

This is an observational database study, not a treatment trial. It will not directly test any therapy, and results may take years to impact patient care.

Conditions

The condition(s) this trial relates to.

achondroplasia Craniofacial Abnormalities Facies hypochondroplasia isolated Pierre-Robin syndrome Muenke syndrome osteogenesis imperfecta Rare Diseases

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.