Eye exercises at home may help control wandering eyes when looking far away
NCT ID NCT07642687
First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This trial tests a 12-week home-based eye training program for children and young adults aged 6 to 25 with intermittent exotropia, a condition where one eye periodically turns outward. The training uses a computer or tablet game with 3D glasses to strengthen near vision control, with the goal of improving eye alignment when looking at distant objects. Some participants wear special reading glasses during training to mimic distance viewing. The study also checks if any improvements last after training stops.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- home-based near vergence training program
- What this could lead to
- If effective, this training could offer a non-surgical, at-home way to improve distance eye control in people with intermittent exotropia.
- What could go wrong
- This is a small, early-phase trial with 42 participants, so results may not apply to everyone. The training requires daily commitment, and benefits may not last after stopping.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Phase
-
Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
-
About 42 people
The number the study aims to enrol. It can still change while the study runs.
- Expected to start
-
Jun 2026
An estimate. Start dates often move.
- Expected to finish
-
Dec 2028
An estimate. End dates often move.
- Lead sponsor
-
Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
-
6 to 25 years
- Sex
-
Anyone
- Healthy volunteers
-
Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria * Age and Diagnosis: Participants must be aged 6 to ≤ 25 years at the time of screening, with a confirmed clinical diagnosis of either Basic or Divergence Excess (DE) Intermittent Exotropia (IXT). * Ocular Alignment Magnitude: Distance exodeviation measuring between 10 and 40 prism diopters (pd) inclusive, determined by the prism and alternate cover test (PACT). * Distance-Near Disparity Limits: Near exodeviation must not exceed the distance exodeviation by more than 10 pd (to exclude Convergence Insufficiency type exotropia). * Baseline Distance Control: A baseline distance IXT Office Control Score (OCS) between Grade 2 and Grade 4 inclusive, based on the mean of 3 standardized assessments. * Baseline Near Control: A baseline near IXT control score less than or equal to the distance IXT control score, based on the mean of 3 standardized assessments. * Visual Acuity: Best-corrected visual acuity (BCVA) of Logarithm of the Minimum Angle of Resolution (logMAR) 0.1 or better in each eye at both distance and near fixation. * Sensory Status: Measurable near stereoacuity of 400 arc seconds or better on the Preschool Randot stereoacuity test. * Refractive Correction Stability: Compliance with wearing a stable, appropriate spectacle correction for ≥ 4 months prior to formal baseline assessment if the participant meets any of the following refractive thresholds: * Myopia \< -0.50D spherical equivalent (SE) in either eye. * Hyperopia \> +2.50D SE in either eye. * Anisometropia \> 1.00 SE. * Astigmatism \> 1.50D cylinder in either eye. * Treatment History: No history of prior non-surgical interventions for IXT, including patching, vision therapy/orthoptics, or overminus lens therapy (≥ 0.50 D). * Surgical History: No prior history of strabismus surgery, extraocular muscle botulinum toxin injections, intraocular surgery, or refractive surgery. * Trial Commitment: No planned strabismus surgery or conflicting ocular therapies during the 24-week study period. Exclusion Criteria * Amblyopia and Co-morbid Strabismus: Presence of amblyopia, nystagmus, restrictive strabismus, or paretic strabismus. * Vertical Misalignment: Presence of an associated vertical ocular deviation \> 5 pd. * Significant Pathologies: Co-existing significant ocular disease or neurological disorders (e.g., cerebral palsy) that could confound oculomotor or sensory evaluations. * Confounding Medications: Regular use of systemic or topical ocular medications known to alter accommodative or vergence function within the 3 months prior to screening (including, but not limited to, atropine, pirenzepine, or systemic anti-epileptic agents).
Get updates
Get notified about this study
Sign up to get updates when this study changes or when new studies for Intermittent exotropia are added.
Genom att skicka in godkänner du våra Användarvillkor
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
-
The places running it
1 site. The list below names each one and where it is.
-
The official record
ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.
-
A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
Contacts and locations
Locations
-
The Optometry Clinic, The Hong Kong Polytechnic University
RECRUITINGHong Kong, Hong Kong
More trials for these conditions
Other studies related to the condition(s) this trial covers.
- Eye exercises may help children with a wandering eye, a trial puts it to the test
- Can 3D movies on a handheld game system help straighten Kids' eyes?
- Could stronger glasses tame wandering eyes in kids?
- Eye muscle surgery showdown: which fix for wandering eyes works best?
- New study tests best glasses for kids with wandering eyes and nearsightedness
- New eye muscle surgery shows promise for correcting outward strabismus