New eye drop shows promise for Graft-Versus-Host dry eye

NCT ID NCT07118254

Recruiting now Disease control Sponsor: Lubris Bio Pty Ltd Source: ClinicalTrials.gov ↗

First seen Nov 01, 2025 · Last updated May 22, 2026 · Updated 31 times

Summary

This study tests whether an eye drop containing a natural lubricant (rhPRG4) can safely and effectively relieve dry eye symptoms in people with ocular graft-versus-host disease (oGVHD), a complication of stem cell transplants. Fifteen adults with moderate to severe dry eye will receive both the active drop and a placebo in random order, each for 28 days. The goal is to see if the active drop improves eye surface damage and symptoms like dryness and burning.

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Contacts and locations

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Study contacts

Contact

Phone: •••-•••-•••• Email: •••••@•••••

Locations

OTA
RECRUITING

Brisbane, Queensland, Australia

Contact Phone: •••-•••-••••
Royal Melbourne Hospital
RECRUITING

Melbourne, Victoria, Australia

Contact Phone: •••-•••-•••• Email: •••••@•••••
Sydney Eye Hospital
NOT_YET_RECRUITING

Sydney, New South Wales, Australia

Contact Phone: •••-•••-•••• Email: •••••@•••••

Conditions

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OCULAR GRAFT-VERSUS-HOST DISEASE