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New vaccine aims to shield seniors from dangerous e. coli infections

NCT ID NCT03819049

First seen May 15, 2026 · Last updated May 22, 2026 · Updated 2 times

Summary

This study tested a new vaccine called ExPEC10V to see if it is safe and can help prevent infections caused by a type of E. coli bacteria outside the intestines. The study included 836 adults aged 60 to 85 who were in stable health. Researchers gave different doses of the vaccine and monitored participants for side effects and immune response to find the best dose for future studies.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • APHP - Hopital Bichat - Claude Bernard

    Paris, 75018, France

  • ATC Pharma

    Liège, 4000, Belgium

  • Anima

    Alken, 3570, Belgium

  • CHRU Tours Hopital Bretonneau

    Tours, 37000, France

  • CHU Lyon Sud

    Pierre-Bénite, 69495, France

  • CHU Nantes

    Nantes, 44093, France

  • Chu Rennes Hopital Pontchaillou

    Rennes, 35000, France

  • Clinical Pharmacology Unit

    Merksem, 2170, Belgium

  • Coastal Carolina Research Center

    North Charleston, South Carolina, 29405, United States

  • EB Flevo Research

    Almere Stad, 1311 RL, Netherlands

  • Hopital Cochin

    Paris, 75014, France

  • Hosp Reina Sofia

    Córdoba, 14004, Spain

  • Hosp. Del Mar

    Barcelona, 08003, Spain

  • Hosp. Univ. La Paz

    Madrid, 28046, Spain

  • Hosp. Univ. Marques de Valdecilla

    Santander, 39008, Spain

  • Hosp. Univ. de La Princesa

    Madrid, 28006, Spain

  • Hosp. Virgen Macarena

    Seville, 41009, Spain

  • Johnson County Clin-Trials

    Lenexa, Kansas, 66219, United States

  • Optimal Research

    Huntsville, Alabama, 35802, United States

  • Optimal Research

    Melbourne, Florida, 32934, United States

  • Optimal Research

    Peoria, Illinois, 61614, United States

  • PRA Health Sciences

    Groningen, NZ 9728, Netherlands

  • Qps-Mra, Llc

    Miami, Florida, 33143, United States

  • Rochester Clinical Research, Inc

    Rochester, New York, 14609, United States

  • Synexus Clinical Research US Inc

    Evansville, Indiana, 47714, United States

  • Synexus Clinical Research US Inc

    Richfield, Minnesota, 55432, United States

  • Synexus Clinical Research US Inc

    Manhattan, New York, 10017, United States

  • Synexus Clinical Research US Inc

    Akron, Ohio, 44311, United States

  • Synexus Clinical Research US Inc

    Columbus, Ohio, 43212, United States

Conditions

Explore the condition pages connected to this study.