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New hope for rare skin Flare-Ups: drug offered to those with no options

NCT ID NCT05239039

First seen Nov 01, 2025

Summary

This program in China gave a single infusion of spesolimab to 39 people with a severe skin condition called generalized pustular psoriasis (GPP) during a flare-up. Participants had no other treatment options available. The goal was to control the flare and monitor for side effects over about 4 months.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • Beijing Friendship Hospital

    Beijing, 100050, China

  • Dermatology Hospital, Chinese Academy of Medical Sciences

    Nanjing, 210000, China

  • Hangzhou Third People's Hospital

    Hangzhou, 310013, China

  • Shandong Provincial Hospital of Dermatology

    Jinan, 250063, China

  • Shanghai Skin Disease Hospital

    Shanghai, 200000, China

  • Southern Medical University Dermatology Hospital

    Guangzhou, 510091, China

  • The First Hospital of China Medical University

    Shenyang, 110001, China

  • The Second Affiliated Hospital Zhejiang University School of Medicine

    Hangzhou, 310009, China

  • The University of Hong Kong-Shenzhen Hospital

    Shenzhen, 518053, China

  • Tianjin Medical University General Hospital

    Tianjin, 30052, China

  • West China Hospital

    Chengdu, 610041, China

  • Wuhan Union Hospital

    Wuhan, 430022, China

Conditions

The condition(s) this trial relates to.

generalized pustular psoriasis psoriasis

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.