Can exercise or ischemic training boost heart health in hypertension?
NCT ID NCT07375407
First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study tested two exercise programs—aerobic exercise and physiological ischemic training—in 60 adults with grade 2 high blood pressure. Over 6 weeks, researchers measured changes in blood markers, fitness, muscle strength, and quality of life. The goal is to see which approach better improves heart health and reduces inflammation.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- aerobic exercise and physiological ischemic training
- What this could lead to
- If successful, this could show that simple exercise programs improve blood vessel health and reduce inflammation in people with high blood pressure.
- What could go wrong
- This is a small, early-stage study with only 60 participants, so results may not apply to everyone. The interventions are short-term (6 weeks), so long-term benefits are unknown.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Phase
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Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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60 people
The number who actually took part.
- Started
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Aug 2023
- Finished
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Feb 2024
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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18 to 65 years
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
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Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: 1. Primary hypertension patients aged 18-65 years 2. Diagnosed with grade 2 primary hypertension 3. Willing to participate in the study Exclusion Criteria: 1. Patients with unstable angina 2. Malignant arrhythmias and high atrioventricular block 3. Unstable hemodynamics 4. Uncontrolled hypertension 5. Acute pericarditis 6. Severe valvular heart disease 7. Chronic obstructive pulmonary disease 8. Cor pulmonale and pulmonary vascular disease 9. Thrombophlebitis 10. Intermittent claudication 11. Cognitive impairment 12. Uncooperative subjects 13. Subjects experiencing infection or inflammation 14. Subjects with neuromuscular disorders that may affect the study results 15. Subjects with musculoskeletal disorders that may affect the study results 16. Complications or comorbidities such as cerebrovascular disease, CAD, atheroma plaques on imaging, heart failure, PAD, and atrial fibrillation.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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Hasan sadikin general hospital
Bandung, West Java, 40161, Indonesia